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Does leflunomide cause weight gain? Medications. According to a 2016 study, people with RA who take the medication leflunomide (Arava) are more likely to experience weight loss. The study examined weight gain and weight loss in more than 30,000 people who were taking RA medication, such as methotrexate, prednisone, or leflunomide.
What are the side effects of leflunomide? Common side effects of Arava include: diarrhea, nausea, stomach pain, loss of appetite, weight loss, headache, dizziness, back pain,
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