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Why is ursodeoxycholic acid used? Bile ducts can become blocked and cause cirrhosis in one or more parts of the liver. Ursodeoxycholic acid is a naturally occurring bile acid which is taken as either a tablet or liquid to try and prevent liver disease in people with cystic fibrosis.
Can ursodiol cause weight gain? Treatment with ursodeoxycholic acid is associated with weight gain in patients with primary biliary cirrhosis. Nevertheless, patients often anecdotally complain of weight gain while on this drug.
What is the function of ursodeoxycholic acid? Ursodeoxycholic acid helps regulate cholesterol by reducing the rate at which the intestine absorbs cholesterol molecules while breaking up micelles containing cholesterol. Because of this property, ursodeoxycholic acid is used to treat (cholesterol) gallstones non-surgically.
What are the four stages of PBC? Liver biopsy also helps stage PBC, which has 4 histologic stages: Stage 1: Inflammation, abnormal connective tissue, or both, confined to the portal areas. Stage 2: Inflammation, fibrosis, or both, confined to the portal and periportal areas. Stage 3: Bridging fibrosis. Stage 4: Cirrhosis.
Is primary biliary cirrhosis fatal? Cirrhosis makes it difficult for your liver to work and may lead to liver failure. It indicates the later stage of primary biliary cholangitis. People with primary biliary cholangitis and cirrhosis have a poor prognosis and higher risk of other complications. Increased pressure in the portal vein (portal hypertension).
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